From Widescreen Gaming Wiki
|Release date||January 14, 2003|
 Game Information
In SimCity 4, you don't just build your city, you breathe life into it. With god-like powers, you sculpt mountains, gouge riverbeds, and seed forests to lay the groundwork for your creation. Then construct the most realistic metropolis you can imagine. Your city comes alive with the hustle and bustle of construction crews, the snarl of traffic and the activity of your Sims. Build mansions on mountainsides, cross canyons with bridges and raise skyscrapers downtown. The impact of your touch will be immediate but not entirely predictable. Cap an erupting volcano to save your city, but don't be surprised if lava explodes from another source. If your citizens burst into a panic, throw down barricades and dispatch the police or send the Mayor's limo to quell the mob. Will your actions calm the crowd or contribute to chaos? With every decision you make, your city and your Sims will respond for better or worse. In SimCity 4 your city pulses with the life that you give it.
 Widescreen Support
SimCity 4 does have native widescreen support. More accurately, SimCity 4 supports custom resolutions. All you need to do is add this to the target of your SimCity4 shortcut:
Just change 1280x720x32 to the resolution you're looking for. Be sure to add the text after the quotation marks of the target. So it should look like:
"C:\Program Files\Maxis\SimCity 4\Apps\SimCity 4.exe" -CustomResolution:enabled -r1680x1050x32
If you're using the Deluxe version, keep in mind that the target will likely be in a different folder:
"C:\Program Files\Maxis\SimCity 4 Deluxe\Apps\SimCity 4.exe" -CustomResolution:enabled -r1680x1050x32
If you're using Steam, add the extra parameter without quotation marks to Launch Options (right-click SimCity 4, select properties) of the game.
However, this may not work always. You may need to change the "Graphics Rules.sgr" with the correctly adjusted settings.
Resolution of 3840x2400 (Viewsonic VP2290b) works only with the very buggy OpenGL driver.
 Supported Resolutions
|1280 x 800 (16:10)|
|1440 x 900 (16:10)|
|1680 x 1050 (16:10)|
|1920 x 1200 (16:10)|
|2560 x 1600 (16:10)|
|1024 x 576 (16:9)|
|1360 x 768 (16:9)|
|1024 x 600 (16:9)|
|1600 x 900 (16:9)|
|1920 x 1080 (16:9)|
|2048 x 1152 (16:9)|
Note that while some resolutions are supported, some clipping of the interface may occur making it impossible to control certain functions, such as "raise mountains" in 1024x600.
 Linux Support
SimCity 4 is known to work with Wine Windows Emulator under Linux. No modifications or special configuration is needed - unless you are using a multi-core system. SimCity 4 has issues with multi-core processors that can cause random crashing.
There are at least two ways to fix this, via terminal or preconfigured Application launcher:
1) "taskset -c 1 wine <path to SC4 exe>" (still had minor crash problem Ubuntu 10.04 64bit).
2) wine "/path/to/SimCity 4.exe" -CPUCount:1 (seems to be more stable Ubuntu 10.04 64bit).
4:3 screenshot: No screenshot currently available
1440 x 900 (16:10) 32 Bit 
The game appears to have a cosmetic bug at high resolutions (>= 1600x1200, reportedly): The images (thumbnails) of large cities in the region have a minor corruption. See e.g. here: http://i15.photobucket.com/albums/a363/phillycheese415/Untitled.jpg EA tech support has claimed that this is the result of NVIDIA driver limitations.
Re-saving a city in a lower resolution fixed the graphics for me, however I assume it will be back after saving in high-res. You can skip the thumbnail generation by saving using Alt-Ctrl-S, however of course that will mean the thumbnail will not reflect changes made to the city since the last "full" save.
Official Site: http://www.ea.com/redesign/games/pccd/simcity4/home.jsp